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depression in its major stages possesses no quickly available remedy: failure of alleviation is one of the most distressing factors of the disorder as...more

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At any rate, during the few hours when the depressive state itself eased off long enough to permit the luxury of concentration, I had recently filled ...more

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The pain of severe depression is quite unimaginable to those who have not suffered it, and it kills in many instances because its anguish can no longe...more

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A phenomenon that a number of people have noted while in deep depression is the sense of being accompanied by a second self — a wraithlike observer wh...more

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The night was blustery and raw, with a chill wet wind blowing down the avenues, and when Rose and I met Françoise and her son and a friend at La Lorra...more

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When I was first aware that I had been laid low by the disease, I felt a need, among other things, to register a strong protest against the word "depr...more

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Depression is a disorder of mood, so mysteriously painful and elusive in the way it becomes known to the self--to the mediating intellect--as to verge...more

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There he must, despite the anguish devouring his brain, present a face approximating the one that is associated with ordinary events and companionship...more

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it has to be emphasized that if the pain were readily describable most of the countless sufferers from this ancient affliction would have been able to...more

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The pain is unrelenting, and what makes the condition intolerable is the foreknowledge that no remedy will come -- not in a day, an hour, a month, or ...more

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The madness of depression is, generally speaking, the antithesis of violence. It is a storm indeed, but a storm of murk. Soon evident are the slowed-d...more

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For those who have dwelt in depression's dark wood, and known its inexplicable agony, their return from the abyss is not unlike the ascent of the poet...more

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This sound, which like all music--indeed, like all pleasure--I had been numbly unresponsive to for months, pierced my heart like a dagger, and in a fl...more

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my brain had begun to endure its familiar siege: panic and dislocation, and a sense that my thought processes were being engulfed by a toxic and unnam...more

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The pain of severe depression is quite unimaginable to those who have not suffered it, and it kills in many instances because its anguish can no longe...more